Munster and Toulouse, who clash at Thomond Park on Saturday, jointly hold the record for most tournament knockout stage qualifications with 19 apiece.

This weekend marks the first time in the history of tournament that a Round of 16 will be played as part of the knockout stage.

Six tournament winners - Exeter Chiefs, Leinster Rugby, Munster Rugby, RC Toulon, Toulouse and Wasps - with 16 Heineken Champions Cup titles between them have qualified for the knockout stage.

Toulouse head coach Ugo Moala says his side have NINE backs unavailable for this game due to injury. The list includes Sofiane Guitoune, who has been ruled out for the remainder of the season.