Courtney Lawes captains an England side that will see Bevan Rodd and Jamie Blamire start in the front row against the Springboks.
Rookie duo Bevan Rodd and Jamie Blamire will start in the front row for England when they face world champions South Africa on Saturday.
Blamire, who has scored four tries in five games for his country, gets his chance from the start with Jamie George ruled out due to a knee injury and prop Rodd comes into the team alongside Kyle Sinckler.
Flanker Courtney Lawes captains the Red Rose for the second time in the absence of Owen Farrell, who suffered an ankle injury in the win over Australia last weekend.
Hooker Nic Dolly could make his debut off the bench as Eddie Jones' side go in search of revenge for the 2019 World Cup final defeat.
Joe Marchant gets the nod to start on the right wing, with Manu Tuilagi moving to inside centre.
Prop Joe Marler is among the replacements, having missed the defeat of the 32-16 of the Wallabies after testing positive for coronavirus.
England have not lost to the Springboks at Twickenham since 2014, when they were edged out 31-18.
England team: Freddie Steward, Joe Marchant, Henry Slade, Manu Tuilagi, Jonny May, Marcus Smith, Ben Youngs; Bevan Rodd, Jamie Blamire, Kyle Sinckler, Maro Itoje, Jonny Hill, Courtney Lawes (captain), Sam Underhill, Tom Curry.
Replacements: Nic Dolly, Joe Marler, Will Stuart, Charlie Ewels, Sam Simmonds, Alex Dombrandt, Raffi Quirke, Max Malins.
